The Column-11-12-2018

Click the title above to open The Column November 2018 European/Asia issue in an interactive PDF format.

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The Column
News

November 12, 2018

Peak Scientific has partnered with Molecular Science Corporation to supply nitrogen gas generation systems on their first mobile laboratory aimed at rapidly expanding the cannabis testing and research sector.

Researchers from the Centro de Investigación y Estudios Avanzados de IPN, in Mérida, Mexico, have investigated the feeding habits of the whale shark (Rhincodon typus) in the Mexican Caribbean using GC–FID.

The Column

Researchers from the University of Almeria have developed a method for the classification of rum using HS-SPME-GC–MS.

The Column spoke to Steven Janvier, a PhD student at Sciensano and Ghent University (Belgium), and Celine Vanhee, a scientist at Sciensano, about their work to develop a hydrophilic interaction chromatography (HILIC) methodology capable of detecting counterfeit polar peptide drugs available on the black market.

News
The Column

November 12, 2018

Agilent Technologies has announced the appointment of Eric Gerber as the company’s new Senior Vice President of strategy and corporate development.

This article presents two case studies regarding the characterization of protein-DNA complexes using two complementary multi-angle light scattering (MALS) techniques, namely size-exclusion chromatography (SEC–MALS) to determine absolute molar mass of each component, and composition-gradient MALS (CG–MALS) to quantify stoichiometry and affinity at binding sites in solution.

Within the broad scope of analytical techniques required to characterize a protein, chromatographic methods have shifted towards high-flow analyses that can drop development time significantly. However, fast analytical methods for charge heterogeneity have lagged in development because current column technologies are ultrahigh-pressure liquid chromatography (UHPLC)-incompatible. This article will demonstrate the development of a high-flow method for charge variant analysis made possible through a bioinert titanium column flow path.

The Column

Carcinogen-containing compounds can develop through some manufacturing processes, such as in the malting process for beer. It is critical to analyze the nitrosamine content in any consumed products as well as monitor the final product. Thermal energy analysis (TEA) is able to quickly identify and analyze N-Nitro, N-nitroso, and nitrogen-containing compounds. This article describes the importance of monitoring these compounds.

In this instalment of the LCGC Blog, solutions for carryover problem in gas chromatography (GC) are considered.