The Column-11-12-2018

The Column

Vol 14 No 11 The Column November 2018 Europe and Asia PDF

November 12, 2018

Issue PDF

14

11

Click the title above to open The Column November 2018 European/Asia issue in an interactive PDF format.

Vol 14 No 11 The Column November 2018 North American PDF

November 12, 2018

Issue PDF

14

11

Click the title above to open The Column November 2018 North American issue in an interactive PDF format.

Peak Scientific and MSC Partner

November 12, 2018

News

14

11

Peak Scientific has partnered with Molecular Science Corporation to supply nitrogen gas generation systems on their first mobile laboratory aimed at rapidly expanding the cannabis testing and research sector.

Investigating Whale Shark Feeding Habits Using GC–FID

November 12, 2018

News

14

11

Researchers from the Centro de Investigación y Estudios Avanzados de IPN, in Mérida, Mexico, have investigated the feeding habits of the whale shark (Rhincodon typus) in the Mexican Caribbean using GC–FID.

Combatting Counterfeit Biopharmaceuticals Using Hydrophilic Interaction Chromatography

November 12, 2018

Cover Story

14

11

The Column spoke to Steven Janvier, a PhD student at Sciensano and Ghent University (Belgium), and Celine Vanhee, a scientist at Sciensano, about their work to develop a hydrophilic interaction chromatography (HILIC) methodology capable of detecting counterfeit polar peptide drugs available on the black market.

Agilent Welcomes Eric Gerber

November 12, 2018

News

14

11

Agilent Technologies has announced the appointment of Eric Gerber as the company’s new Senior Vice President of strategy and corporate development.

Characterizing Protein-Nucleic Acid Conjugates with Light Scattering

November 12, 2018

Features

14

11

This article presents two case studies regarding the characterization of protein-DNA complexes using two complementary multi-angle light scattering (MALS) techniques, namely size-exclusion chromatography (SEC–MALS) to determine absolute molar mass of each component, and composition-gradient MALS (CG–MALS) to quantify stoichiometry and affinity at binding sites in solution.

High-Flow Weak Cation Exchange for Charge Variant Analysis

November 12, 2018

Features

14

11

Within the broad scope of analytical techniques required to characterize a protein, chromatographic methods have shifted towards high-flow analyses that can drop development time significantly. However, fast analytical methods for charge heterogeneity have lagged in development because current column technologies are ultrahigh-pressure liquid chromatography (UHPLC)-incompatible. This article will demonstrate the development of a high-flow method for charge variant analysis made possible through a bioinert titanium column flow path.

Looking for Carcinogenic Nitrosamine Compounds in Beer

November 12, 2018

Features

14

11

Carcinogen-containing compounds can develop through some manufacturing processes, such as in the malting process for beer. It is critical to analyze the nitrosamine content in any consumed products as well as monitor the final product. Thermal energy analysis (TEA) is able to quickly identify and analyze N-Nitro, N-nitroso, and nitrogen-containing compounds. This article describes the importance of monitoring these compounds.