The Column-12-08-2020

Implementing Pharmacopeial Methods —Method in the Madness?

December 08, 2020

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Incognito leads us through the complex method used to determine related substances for hydroxychloroquine, exploring the practical implementation and critical evaluation of a less than optimum ultrahigh-pressure liquid chromatography (UHPLC) pharmacopeial method.

Developments in Field‑Flow Fractionation Coupled to Light Scattering

December 08, 2020

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Field-flow fractionation (FFF) coupled to light scattering is a powerful method to separate and characterize nanoparticles, proteins, and polymers from a few nanometres to a few micrometres. The technique is one of the few that can cover the full size range of nanomaterials and provide high-resolution size distributions and additional characterization. New developments in FFF enhance performance and productivity.

The LCGC Blog: 10 Great Tips for Electrospray Ionization LC–MS

December 08, 2020

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Here are 10 great tips for optimizing LC-Electrospray Ionization (ESI)-MS so that you achieve the best possible results every time. These tips and tricks have been collated by my colleagues to form a beginner’s guide to LC-(ESI)MS and as a primer for those who are already using the technique.

New US EPA Dioxin Method Approved

December 08, 2020

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Agilent Technologies has announced that their collaboration with SGS has resulted in a new GC-TQ method.