LCGC Europe-02-01-2020

LCGC Europe

Vol 33 No 2 LCGC Europe February 2020 Regular Issue PDF

February 10, 2020

Issue PDF

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Click the title above to open the LCGC Europe February 2020 regular issue, Volume 33, Number 2, in an interactive PDF format.

Paper-Based Sorptive Phases Prepared by Dip Coating

February 01, 2020

Peer Reviewed

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Paper-based sorptive phases are promising tools in sample preparation because of their high surface-to-volume ratio, porosity, and versatility. This article discusses the synthesis of paper-based sorptive phases by dip coating. This procedure has allowed a wide variety of phases coated with polymers, nanoparticles, and their combination to be synthesized. This article presents the synthesis, types of coatings, and extraction devices, to highlight the versatility and potential of these materials to the analytical community, particularly for sample preparation.

Sampling: The Ghost in Front of the Laboratory Door

February 01, 2020

Peer Reviewed

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Sampling can be the most demanding part of an analysis. Anybody in charge of sampling needs a good understanding of the composition of the material to be investigated, its heterogeneity (or homogeneity, in simple cases), and the chemical properties of the analytes. Sampling procedures must be described in detail. Detecting the bias of a sampling procedure can be difficult; this fact is trivial, but it must not be forgotten.

State-of-the-Art in Capillary Liquid Chromatography: Now, Next, and How?

February 01, 2020

Column Watch

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The “State-of-the-Art in Capillary Liquid Chromatography” panel discussion at the 43rd International Symposium on Capillary Chromatography (ISCC 2019) in Fort Worth, Texas, USA, was a thoughtful dialogue on current challenges and potential future directions in the field. The session included a general overview of the current state of the field, key drawbacks preventing widespread use of capillary liquid chromatography (LC) columns, and how these challenges might be overcome. In this article, we highlight some of the common themes that were discussed as part of this panel.

Size-Exclusion Chromatography for the Analysis of Complex and Novel Biotherapeutic Products

February 01, 2020

Biopharmaceutical Focus

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This study presents applications of size-exclusion chromatography (SEC) for characterization and quality control of novel biotherapeutic products, including antibody–drug conjugates, hydrophobic proteins, and coformulations. Examples of modifying SEC mobile-phase composition and running conditions to modulate the separation are discussed, as well as approaches and strategies for analyzing atypical protein products such as coformulations.

Analytica 2020

February 01, 2020

Events

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The International Trade Fair for Laboratory Technology, Analysis, Biotechnology and Analytica Conference 2020 will take place in the International Congress Center (ICM), Munich, Germany, from 31 March to 3 April 2020.