LCGC Europe-04-01-2006

When a problem is not solved quickly, it is a good idea to go back to basics and determine if the equipment is functioning properly or not.

An increasingly available and attractive clinical analysis method, LC?MS nevertheless fails to directly benefit from the knowledge and experience of clinicians steeped in the immunoassay tradition.

Overall FID sensitivity depends upon the combustion gas flow-rates, the carrier-gas flow-rate, the flame jet exit diameter, the relative positions of jet and collector and, to a lesser degree, the detector temperature.

Is it possible to combine a serious scientific meeting together with social events and fun? Well if it is possible then the ExTech and HTC-9 meeting held in York, UK between 6?10 February came very close.

Biologists entering liquid chromatography?mass spectrometry (LC?MS) from a background of general LC rarely use their mass spectrometer to its full potential. Isotope peaks offer huge possibilities both in semi-quantitative interpretation of structure and in quantitative labelling studies. This article examines charge state, "easy" isotopes, such as chlorine, the slightly harder problem of sulphur compounds, and finally looks at a method for improved measurement of heavy labels in a metabolic study.

Sony has released details of its new e-book reader using E-Ink technology. This could transform the electronic reading experience. The lightweight reader could bring a whole new meaning to "book smart".

The department of Chemistry and Chemical Biology at Harvard University has purchased a site licence of the ACD/2D NMR processor. The Advanced Chemistry Development (ACD/Labs) processor will be deployed to all faculty staff and students for use on department-owned or leased computers as well as personal PCs.