LCGC Europe-11-01-2013

LCGC Europe

A Multimodal Liquid and Supercritical Fluid Chromatography Chiral Separation Screening and Column Maintenance Strategy Designed to Support Molecules in Pharmaceutical Development (Part 1)

November 01, 2013

Cover Story

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Chiral separation screening has become a widely accepted approach for the rapid identification of an appropriate chiral stationary phase for use in more focused enantioseparation optimization. A set of extended screens encompassing various chromatographic modes using HPLC and SFC is presented.

Practical Gas Chromatography (GC)

November 01, 2013

GC Connections

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Questions about how practical proposed gas chromatography (GC) method changes are often come up during optimization for speed and resolution, or while converting to a different carrier gas. Related objective measurements such as the optimum practical carrier gas velocity were defined more than 40 years ago. This instalment reviews such metrics in the light of their relevance to today's GC challenges.

The Top 10 HPLC and UHPLC Column Myths: Part 2

November 01, 2013

Column Watch

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In the final part, the top 10 HPLC and UHPLC column myths are presented and attempts are made to demystify them by offering some evidence that they are untrue. This part will feature myths five to one.

Mobile Phase Optimization Strategies in Reversed-Phase HPLC

November 01, 2013

The Essentials

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There are many ways to improve retention or selectivity in reversed-phase HPLC and knowledge of the key eluent variables to achieve this is essential reading.

Events

November 01, 2013

Departments

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Events

Vol 26 No 11 LCGC Europe November 2013 Regular Issue PDF

November 01, 2013

Issue PDF

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Click the title above to open the LCGC Europe November 2013 regular issue, Vol 26 No 11, in an interactive PDF format.