LCGC-North America-05-01-2021 | LCGC North America

Going Low: Understanding Limit of Detection in Gas Chromatography (GC)

May 01, 2021

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The limit of detection (LOD) of an analytical method may be defined as the smallest concentration of analyte that has a signal significantly greater than that of a blank sample signal. We explore the sources of experimental uncertainty and variability in LOD determinations.

An Opportunity for Industrial–Academic Partnerships

May 01, 2021

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Recently, the concept of environmental and social corporate governance (ESG) has received greater focus, particularly in the oil and gas industry. Its implementation offers opportunities for analytical chemists to help achieve greater sustainability.

Where Has My Efficiency Gone? Impacts of Extracolumn Peak Broadening on Performance, Part II: Sample Injection

May 01, 2021

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Dispersion of analyte peaks outside of chromatography columns can seriously erode the resolution provided by good columns. Here, we focus on the contribution of the sample injection step to the total level of extracolumn dispersion in an LC system.