- About
- Advertise
- Author Guidelines
- Contact MJH
- Editorial Advisory Board
- Ethics Policy
- Do Not Sell My Personal Information
- LCGC Staff
- Privacy Policy
- Permissions
- Subscriptions
- Terms and Conditions
© 2023 MJH Life Sciences™ and Chromatography Online. All rights reserved.
LCGC North America-07-01-2015
LCGC North America
Distorted Peaks – A Case Study
July 01, 2015
LC Troubleshooting
33
7
The potential causes are considered for peak distortion for the first two peaks in the chromatogram.The potential causes are considered for peak distortion for the first two peaks in the chromatogram.
Aiding the Development of Extraction Procedures with Response Surface Methodology
July 01, 2015
Sample Prep Perspectives
33
7
When developing analytical methods, several parameters are often considered, things like solvent type and amount, sample size, pH, sorptive phases, temperature, time, and more. While some of these considerations can be considered unimportant in a given situation and experience and chemical knowledge can guide us to appropriate starting points, extraction method development is often a one-parameter-at-a-time proposition. A family of statistical approaches, which fall under the category of response surface methodology, are available to screen and optimize several parameters simultaneously.
Flame Ionization: GC's Workhorse Detector
July 01, 2015
GC Connections
33
7
As the flame ionization detector (FID) approaches its 60th anniversary in 2017, this installment examines the crucial role that it has played and continues to play for all types of gas chromatography. Without the FID, the early development of gas chromatography (GC) would have proceeded more slowly especially in the petroleum industry and related hydrocarbon application areas.
Gradient HPLC—One Invaluable Equation
July 01, 2015
The Essentials
33
7
Here, we concentrate on one particularly useful equation that allows us to make changes to an analytical system to improve throughput or efficiency, while retaining the selectivity of the original method.
A Decade of Quantitating Cyanide in Aqueous and Blood Matrices Using Automated Cryotrapping Isotopic Dilution Static Headspace GC–MS
July 01, 2015
Peer-Reviewed Article
33
7
The author shares his insights into the principles and practice of implementing and improving upon the original method to quantitate cyanide at trace concentration levels in human blood matrices using automated cryogenic trapping isotope dilution static headspace gas chromatography–mass spectrometry (GC–MS).
Challenges in the Determination of Protein Aggregates, Part II
July 01, 2015
Biotechnology Today
33
7
Here in part II of our series on assessing protein aggregation, we provide an overview of best practices for achieving this goal, including the importance of using a multimethod approach.Here in part II of our series on assessing protein aggregation, we provide an overview of best practices for achieving this goal, including the importance of using a multimethod approach.
LCGC App of the Month CEToolbox
July 01, 2015
App of the Month
33
7
The CEToolbox app is designed as a calculator for capillary electrophoresis.
Vol 33 No 7 LCGC North America July 2015 Regular Issue PDF
July 01, 2015
Issue PDF
33
7
Click the title above to open the LCGC North America July 2015 regular issue, Vol 33 No 7, in an interactive PDF format.