LCGC North America-08-01-2014

Recent developments have made organic polymer monoliths much more suitable for the separation of small molecules.

Mechanical strength, acid and alkaline durability, loadability, and overload characteristics are a few of the parameters evaluated.

When transferring a method between HPLC and UHPLC, various potential pitfalls may result in selectivity differences, changes in efficiency, and failure to meet resolution system suitability criteria.

Because of improved technologies and other changes in modern HPLC, these seven common practices are now highly questionable.

Small changes in retention time with an LC method are normal. At what point is a problem suggested?

What are the characteristics and relevant considerations for the development and validation of a stability-indicating method?

An overview of the analytical approaches used for the analysis of biomolecules

Click the title above to open the LCGC North America August 2014 regular issue, Vol 32 No 8, in an interactive PDF format.