LCGC North America-10-01-2012

Professor Mary Wirth and graduate students Bingchuan Wei and Benjamin Rogers from Purdue University demonstrate a quantum leap in protein column efficiency. Using colloidal silica particles of submicrometer diameters (470 nm), they obtained plate heights that were as much as 15-fold lower than the theoretical limit for Hagen-Poiseuille flow.

Sample preparation in this study involved QuEChERS extraction followed by a filter-based cleanup method that is easier and faster than dispersive solid-phase extraction.

LCGC North America
GC Connections

October 01, 2012

SPME decouples sampling from matrix effects that would distort the apparent sample composition or disturb the chromatographic separation. It is also easy to use and reduces solvent consumption.

The Essentials
LCGC North America

October 01, 2012

An overview of the principles and equipment required for scaling analytical separations to the preparative scale and considerations for the scale of analyte required.

LCGC North America
LC Troubleshooting

October 01, 2012

A closer look at how the solvent chosen for injection can affect the appearance of chromatographic peaks.

Issue PDF
LCGC North America

October 01, 2012

Click the title above to open the LCGC North America October 2012 regular issue, Vol 30 No 10, in an interactive PDF format.