LCGC North America-11-01-2013

The use of a monolithic column reduces analysis time in an on-line biopharmaceutical HPLC analysis of granulocyte colony stimulating factor.

With accountability and regulatory compliance being such a large part of the modern laboratory, the necessity for a laboratory information management system (LIMS) cannot be understated.

How to evaluate a calibration curve and calculate the lower limit of calibration.

Correlating biological activity with chemical composition is the Holy Grail of natural product chemists. Is mass spectrometry the right tool for this challenge?

Some sample preparation techniques that were introduced in the past are now being used for new applications.

There are many ways to improve retention and selectivity in reversed-phase HPLC separations. Choosing the correct mobile phase is maybe the most important step.

A discussion of the effects of increased carrier-gas flow in an example separation that includes two pairs of solutes.

A new chromatography-based method for analyzing a traditional Chinese medicine and its metabolites.

The Coblentz Society, an affiliate of the Society of Applied Spectroscopy, was approached with a challenge from an anonymous donor during the SciX13 conference.

Click the title above to open the LCGC North America November 2013 regular issue, Vol 31 No 11, in an interactive PDF format.