October 2022 | LCGC North America

Analytical Characterization of Host Cell Proteins (HCPs)

October 01, 2022

Column: Focus on BioPharmaceutical Analysis

40

10

In response to regulatory concerns, host cell protein (HCP) analysis is now often conducted using LC–MS/MS. Unlike ELISA, LC–MS/MS can positively identify and quantify specific HCPs and characterize the total amount of HCPs present.