Current Trends in Mass Spectrometry

The benefits of IMS-MS for quantitative proteomics, including enhanced sensitivity, improved selectivity, and reduced interference, are discussed.

A high-level assessment of the sustainability of the SIFT-MS technique and its automated variant is conducted using White Analytical Chemistry (WAC) principles.

This study highlights the promising potential of LC–MS as a powerful tool for mAb quality control within the context of upstream processing.

LCGC International spoke to Craig Wheelock and Matthew Smith from the Wheelock Laboratory at the Karolinska Institute, Sweden, about a novel desorption electrospray ionization–multiple-reaction-monitoring mass spectrometry (DESI-MRM-MS) workflow his team has developed to spatially map oxylipins in pulmonary tissue.

This article explores the integration of high-resolution ion mobility spectrometry–mass spectrometry (HRIMS-MS) with liquid chromatography (LC) and quadrupole time-of-flight mass spectrometry (QTOF-MS) as a comprehensive workflow for PFAS analysis.

This information is supplementary to the article “Accelerating Monoclonal Antibody Quality Control: The Role of LC–MS in Upstream Bioprocessing”, which was published in the May 2025 issue of Current Trends in Mass Spectrometry.