LCGC Advances in Biopharmaceutical Analysis

An introduction from our guest editors.

Innovative native separation strategies coupled with native mass spectrometry techniques to characterize biopharmaceuticals close to their natural state are described.

A novel method to simultaneously characterize the capping and poly(A) tail for therapeutic mRNA in a single sample preparation workflow is described.

The authors discuss key findings from recent biosimilarity assessments they conducted on biosimilars of granulocyte-colony-stimulating factor (G-CSF), insulin glargine, rituximab, and trastuzumab.

An interview with Reed Harris on critical quality attributes and other contemporary trends in biopharm analysis.