Advances and Challenges in Separation Science
A session titled ?Advances and Challenges in Separation Science? chaired by Professor Engewald, Leipzig, Germany, begins at 2:00 p.m. today.
Room B21 (Hall B2)14:00
A session titled ‘Advances and Challenges in Separation Science’ chaired by Professor Engewald, Leipzig, Germany, begins at 2:00 p.m. today. The session will begin with the Gerstel prize award ceremony and winners presentation.
The discussion will start with a presentation on the ‘Supercritical Fluid Chromatography: Past, Present and Future’ by Pat Sandra of the Research Institute for Chromatography, Kortrijk, Belgium. The use of carbon dioxide as a major as well as a minor mobile phase constituent will be discussed in terms of chromatographic performance and a comparison will be made with the recent developments in LC.
This will be followed by a talk on ‘High-Temperature Liquid Chromatography – Advances, Challenges and Limitations’ by Thorsten Teutenberg of the Institute for Energy and Environmental Technology, Duisburg, Germany. In this presentation, the advances in the field of high-temperature liquid chromatography, as well as the challenges and limitations of this technique, will be discussed.
After a short half-hour interval in the proceedings a lecture will follow by Jörg P. Kutter of the Technical University of Denmark, Lyngby, Denmark, on the ‘Carbon nanotubes as stationary phase materials for miniaturized separation system’. Design considerations, applications examples and performance results will be discussed during the presentation.
Following this will be a talk on ‘Analytical Strategies for Metabolomics’, led by Katja Dettmer, Regensburg, Germany.
The session closes with a presentation by Wolfgang Goetzinger, Cambridge, USA, on ‘A New Approach to Increase Volume Loading for Semi-preparative RP Gradient Separations of Small Molecules’. Goetzinger will present the improvements that “at-column dilution” has brought to semi-preparative applications and highlight a few instrument considerations that are important to avoid pitfalls with this approach. In addition he will suggest an alternative to this approach that provides similar results without the need for increased instrument complexity.
Measuring Lavender Essential Oil’s Effect on Cancerous Tumors with GC-MS
January 15th 2025A recent study aimed to investigate the impact of lavender essential oil (LEO) and of its terpenic components on the properties of glioblastoma (GBM) cells in an in vitro model. The study demonstrated that LEO induces a proliferation slowdown and an impairment of cell migration of GBM cells besides reducing oxidative stress.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
SPE-Based Method for Detecting Harmful Textile Residues
January 14th 2025University of Valencia scientists recently developed a method using solid-phase extraction (SPE) followed by high-performance liquid chromatography coupled to high-resolution mass spectrometry (HPLC–HRMS/MS) for detecting microplastics and other harmful substances in textiles.
