In this application, simple and complex carbohydrates, which are often analyzed by HILIC, are separated on the BEH Amide column and then directly detected with electrospray ionization mass spectrometry (ESI-MS) with no need for derivatization, post-column addition, or metal complexing agents.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.