Mass spectrometry can teach core chemistry concepts beyond technique training or product characterization, though adoption barriers remain.
|Articles|October 14, 2020
Analysis of IgdE Digested Monoclonal Antibody Fragments
Author(s)Phenomenex, Inc.
IgdE allows for better characterization of the antibody and yields an intact Fc and an intact Fab fragment that can be further isolated and characterized.
Related to this article
Automated sequential tube sampling and chemometrics supplement GC–MS, adding time profiling and fast product-line comparison for real-world insight.
Ultrahigh-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) tracks blood metabolite changes after repetitive transcranial magnetic stimulation (rTMS)-cognitive training therapy.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.
SFC Europe 2026 brings global experts to Basel for courses, scientific talks, workshops, and insights into greener separation technologies.
A novel SFC–QTOF-MS method accurately detected 10 drugs in oral fluid, matching LC–MS/MS in 83 DUID cases while reducing run time by 42% and organic solvent use by 81%.
Supercritical fluid extraction (SFE) and high-pressure liquid chromatography (HPLC) team up to recover olive waste antioxidants. Marina Russo of the University of Messina (Italy) discusses the details.
Waters' Erin Chambers says combining column chemistry and particle-physics innovation cut a GLP-1 impurity profiling workflow from three hours to under one.