Analytica 2016 Tuesday Afternoon Sessions
Session Title: Structural “Omics” (Room 02)
Chairman: Prof. Dr. C. Borchers
12:00 –
K. Pagel:
Glycomics in a Wind Tunnel - Ion Mobility-Mass Spectrometry of Isomeric Glycans and Glycopeptides
12:30 –
F. Liu:
Proteome-wide Profiling of Protein Assemblies by Cross-linking Mass Spectrometry
13:00 –
E. Petrotchenko:
Solving Protein Structures by Structural Proteomics
13:30 – Break
Session Title: Liquid Profiling/Liquid Biopsy (Room 04a)
Chairman: Prof. Dr. D. Teupser
12:00 –
V. Haselmann:
Circulating Tumor DNA (ctDNA): Diagnostic and Technical Promises and Challenges
12:30
–
W. Schmiegel:
Liquid Biopsy – What is the Relevance?
13:00
–
M.W. Gutowska-Ding:
Good or Bad Sequencing Data? Setting a Benchmark for the Quality of Diagnostic NGS in the Laboratory
13:30 – Break
Session Title: Separation Techniques: How Many Dimensions Are Enough? (Room 05)
Chairman: Prof. Dr. O. J. Schmitz
12:15 –
T. Moritz:
Mass Spectrometry- based Metabolomics: Not MS Only
12:45 – Award Session: Eberhard-Gerstel-Award (Room 05)
Session Title: Rudolf Bock Memory Lecture (Room 05)
Chairman: Prof. Dr. R. Nießner
13:15 –
W. Dünges:
Comprehensive Microchemical Methods in the nL/μL-Range
Session Title: Separation Techniques: How Many Dimensions Are Enough? (Room 05)
Chairman: Prof. Dr. O. J. Schmitz
14:00 –
P. Schoenmakers:
Increasing the Resolution, Speed, and Sensitivity of Separations
14:30 –
T. Teutenberg:
Optimization of the Separation Space and Separation Time in Online LC x LC – How Fast Can We Go?
15:00 –
O. J. Schmitz:
Ion Mobility Spectroscopy as a Powerful Separation Dimension in LC–MS
15:30 – Break
16:00 –
D. Stoll:
Making the Most of the Second Dimension in Two-Dimensional Liquid Chromatography
16:30 – M. Thevis:
Recent Examples for the Utility of Chromatography, Ion Mobility, and Mass Spectrometry in Sports Drug Testing
Session Title: Foodomics - Tools for Comprehensive Food Analysis (Room 03)
Chairman: Prof. Dr. P. Schmitt-Kopplin
12:00 – C. Roullier-Gall:
Chemical Message in a Bottle: Metabolomics Characterization of the Wine Composition
12:30 – J. Luetjohann:
Pesticide Metabolomics: Screening of Plant-Derived Commodities for Pesticide Metabolites by UHPLC-HR-QToF-MS
13:00 – Break
Session Title: “OMICS” Towards Personalized Medicine (Room 02)
Chairman: Prof. Dr. A. Sickmann
14:00 –
C. Borchers:
Quantifying Signalling Pathway Activity Using Immuno-MALDI
14:30 –
J.R. Yates:
Understanding Disease Using Mass Spectrometry
15:00 – T. Guo:
Rapid and High-Throughput Protein Quantification from Biopsy-level Tissues Using PCT-SWATH
15:30 – Break
16:00 –
N.L. Kelleher:
Native and Denatured Modes for Interrogation of Whole Proteins and Protein Complexes by Top Down Proteomics
16:30 –
J. Van Eyk:
Proteome-Centric Requirement for Precision Medicine and Understanding Pathological Diversity
17:00 –
O. Poetz:
Monitor Preterm Infant Organ Maturity by Plasma Proteins
Session Title: Clinical Application of Mass Spectroscopy (Room 04a)
Chairman: Prof. Dr. M. Vogeser and Prof. Dr. U. Ceglarek
14:00 –
C. Rizzo:
Mass Spectrometry in Paediatric Laboratory Medicine
14:30 –
J.W. Alffenaar:
Modern TDM by MS
15:00 – A. Gaudl:
Quantitative Steroid Analysis in Body Fluids and Hair: One Method to Rule Them All
15:30 – Break
Session Title: Analytical Toxicology Update (Room 04a)
Chairman: Dr. J. Hallbach and Prof. Dr. K. Rentsch
16:00 –
H. John:
Identification of Novel Sulfur Mustard Adducts with Implications for Verification and Toxicological In Vitro Testing
16:20 –
K.M. Rentsch:
The Role of LC–MS in Clinical Toxicology
16:40 –
J. Hallbach:
Is GC–MS Still a Working Horse in Analytical Toxicology?
Session Title: Emerging Contaminants – Novel Analytical Concepts (Room 03)
Chairman: Prof. Dr. M. Rychlik
14:00 – C. Dall’Asta:
Modified Mycotoxins: Formation, Occurrence, and Relevance in Food
14:30 – S. Uhlig:
Fungal Polyketides: 2-Amino-14,16-Dimethyloctadecan-3-ol, Its History, Biosynthesis, and Biological Effects
15:00 – R. Maul:
Phomopsins – Toxic Secondary Metabolites Formed by Diaporthe toxica on Various Legumes
15:30 – Break
16:00 –
C. Gottschalk:
Pyrrolizidine Alkaloids - A New Threat for Food and Feed Safety?
16:30 – T. Stahl:
Studies on the Paths of entry of Per- and Polyfluorinated Alkyl Substances (PFAS) in Foodstuffs and in the Food Chain by the use of LC–MS–MS
17:00 – F. Habedank:
Disclosure of Pesticide Metabolites by Reprocessing Full Scan Data of Macp Routine Samples
Session Title: Resource Analysis
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The Constant Companion of all Activities along the Value-Added-Chain (Room 04b)
Chairman: Dr. A. Renno
14:00 –
C. Wagner:
A Scientific Basis for Representative Sampling – Theory of Sampling
14:30 – R. Möcke:
State-of-the-Art Quantitative Mineral Phase Determination of Resource Materials by XRD
15:00 – D. Sandmann:
Development and Application of SEM-based Mineral Liberation Analysis
15:30 – Break
16:00 –
J.D. Pedarnig:
Application of Laser Induced Breakdown Spectroscopy to the Analysis of Secondary Materials in Industrial Production
16:30 –
A. Müller:
Chemical Characterization of Natural High-purity Quartz Deposits – The Source of High-tech Products
17:00 –
M. Maiwald:
Process Analytical Technology for Resource Analytics – The Role of Reference Materials
Measuring Procyanidin Concentration in Wines Using UHPLC
January 24th 2025Researchers from the University of Bordeaux (Villenave d'Ornon, France) report the development and validation of a rapid and quantitative analytical method measuring crown procyanidin concentration in red and white wines using ultra-high performance liquid chromatography (UHPLC) coupled with a ultra-high performance liquid chromatography (Q-TOF) mass spectrometer.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Testing Solutions for Metals and PFAS in Water
January 22nd 2025When it comes to water analysis, it can be challenging for labs to keep up with ever-changing testing regulations while also executing time-efficient, accurate, and risk-mitigating workflows. To ensure the safety of our water, there are a host of national and international regulators such as the US Environmental Protection Agency (EPA), World Health Organization (WHO), and the European Union (EU) that demand stringent testing methods for drinking water and wastewater. Those methods often call for fast implementation and lengthy processes, as well as high sensitivity and reliable instrumentation. This paper explains how your ICP-MS, ICP-OES, and LC-MS-MS workflows can be optimized for compliance with the latest requirements for water testing set by regulations like US EPA methods 200.8, 6010, 6020, and 537.1, along with ISO 17294-2. It will discuss the challenges faced by regulatory labs to meet requirements and present field-proven tips and tricks for simplified implementation and maximized uptime.