Liquid chromatography–ion mobility spectrometry–high-resolution mass spectrometry (LC–IMS–HRMS) shows elephant seal pups carry more PFAS than their mothers do.
News|Articles|October 21, 2025
Applying Analytical Quality by Design Principles to Biopharma Method Development and Optimization
Author(s)Waters Corporation
Applying Analytical Quality by Design (AQbD) principles to impurity method development enables robust, science-based strategies for characterizing and controlling critical quality attributes in protein therapeutics. This webinar will present a case study on developing a fluorescence-based (FLR) method for quantifying Mannose-5 glycans, demonstrating how risk-based design and systematic evaluation of method parameters enhance reliability, reproducibility, and product understanding across the biopharmaceutical lifecycle.
Related to this article
Gas chromatography–mass spectrometry (GC–MS) and omics profiling distinguish duck and goose foie gras composition.
This week's Chromatography Online highlights include olive waste antioxidant recovery, food and tea analysis, EV isolation, mRNA vaccine purification, perfusion chromatography for oligonucleotides, mass spectrometry in teaching and career advice from “Women in Chromatography.”
Kinjal Bhatt and Ina Varfaj call AI a chromatography equalizer only if training and access keep pace, framing the risk as implementation, not technology.
Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS) reveal lasting brain cholesterol loss after myelin damage.
Metrohm USA's IONIC Titrator offers cloud access and a 10-inch touchscreen.
Chromatography and spectrometry were used in tandem to reveal how ultrasound boosts chicken soup flavor compounds.
Kinjal Bhatt would expose early-career scientists to the field sooner, while Ina Varfaj says a broken chromatography column taught her failure is normal.