Gas chromatography–mass spectrometry (GC–MS) and ion chromatography profile wasabi and mustard heat and acidity.
News|Articles|January 21, 2026
Efficient Method Development for Separation of Antibody Charge Variants by Ion-Exchange Chromatography
Author(s)Shimadzu Corporation
This article describes how to efficiently achieve the optimal peak separation for charge variants of a monoclonal antibody using pH gradient ion-exchange chromatography and LabSolutions MD, dedicated software that can automate the entire method development workflow, including the generation of an analysis schedule, mobile phase preparation, and data processing.
Related to this article
How feasible is it to integrate this Bayesian graph-theory methodology into existing commercial chromatography software workflows for semi-automated data curation in routine analytical laboratories?
Reversed-phase high-performance liquid chromatography (RP-HPLC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) show frequent milking alters cobra venom toxin makeup.
Gabriel Vivó-Truyols outlines the benefits and challenges of combining graph theory with Bayesian statistics to automate peak assignment and alignment.
This week, Chromatography Online’s coverage spanned lipidomics-based early cancer detection, career paths in separation science, machine learning and uncertainty-driven approaches to LC method development, new EU wastewater rules for pharmaceutical micropollutants, automated Separation Quality Factor (SQF) evaluation in chromatography data systems, and solutions to GLP-1 peptide analysis challenges.
Gabriel Vivó-Truyols from the Spanish Council for Scientific Research, Madrid, Spain. discusses his work on using graph theory and Bayesian statistics for peak assignment and chromatographic alignment.
Gas chromatography (GC) analysis ties prenatal mindfulness to shifts in placental fatty acids.
Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography-quadrupole time-of-flight mass spectrometry (LC–qTOF–MS) reveal metabolic shifts in tricuspid regurgitation.
Trending on LCGC International
1
GLP-1 Peptide Analysis: Challenges and Solutions
2
AI/ML Now: Uncertainty-Driven Model-Based Search Methods for Method Development in Liquid Chromatography (Part Two)
3
Industry Roundup: Waters Posts Strong Third Quarter as LC–MS and Chromatography Consumables Drive Growth, Acquires Ion Mobility Pioneer MOBILion
4
GC–MS Probes Acidity and Heat in Wasabi, Mustard
5