ASMS 2021 Tuesday Morning Session: Small Molecules–Quantitative Analysis


The ASMS 2021 Tuesday morning oral session titled “Small Molecules: Quantitative Analysis,” will be held from 8:30 to 10:30 am in room 113 ABC. The session, chaired by Christopher G. Gill of Vancouver Island University in Nanaimo, British Columbia, Canada, and presided by Scott Borden, also of Vancouver Island University, includes a discussion on a variety of topics relating to small molecules.

Jeremiah Jamrom of Duquesne University will kick off the session with a talk on isotopic quantification technology of dried blood cards for biomarkers such as methlymalonic acid and vitamin D.

Next, Ana Celia Grenier of Dominion Diagnostics will address strategies to identify and mitigate interferences in urine drug testing using liquid chromatography–tandem mass spectrometry (LC–MS/MS) methods.

In the third talk, Emma Guiberson of Vanderbilit University will discuss the use of matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) and LC–MS/MS to investigate bile acid abundance changes during infection with Clostridioides difficile, and the impact of cholestyramine on spore germination efficacy.

Pierre Picard of Phytronix Technologies will present a study of the use of cranberries to prevent urinary tract infections (UTIs). He and his team developed a high-throughput method to quantify the metabolites of cranberry proanthocyanidins (PACs) in urine

Quantitative analysis of neonicotinoid pesticide biomarkers in human urine by solid-phase extraction and HPLC–MS/MS is the topic of the following talk, by Wenjing Xi of the State Hygienic Laboratory at the University of Iowa.

The session will wrap up with a presentation by Ting-Jia Gu of the School of Pharmacy at the University of Wisconsin-Madison on the quantitative analysis and structural elucidation of fatty acids that are involved in many biological pathways.

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