Best of the Week: The Latest from ASMS 2025

This week, LCGC International published a variety of articles on the latest happenings from ASMS 2025. Below, we’ve highlighted some of the most popular articles that were published this week.

Agilent Introduces Advanced LC-MS and Miniaturized GC-MS Technologies at ASMS 2025

Caroline Hroncich

At the 73rd American Society for Mass Spectrometry (ASMS) conference in Baltimore, Maryland, Agilent introduced new mass spectrometry (MS) technologies aimed at advancing critical sectors such as biopharmaceutical development and clinical diagnostics. The announcements were made during a joint press release and live press conference held on Monday at the event. Agilent unveiled several key technologies, including the InfinityLab Pro iQ Series, which comprises the Pro iQ and Pro iQ Plus—liquid chromatography-mass spectrometry (LC-MS) systems designed to support a wide range of applications, from small molecule analysis to complex biomolecules such as oligonucleotides, peptides, and proteins. Agilent showcased the 8850 GC, a compact gas chromatography (GC) system now compatible with both single and triple quadrupole mass spectrometry, delivering high-speed performance in a small GC-MS format.

Jack Henion Highlights Collaborative Efforts Driving LC–MS Breakthroughs at ASMS

Caroline Hroncich

Speaking Monday at the American Society for Mass Spectrometry (ASMS) conference in Baltimore, Maryland, Jack Henion—a pioneering figure in analytical chemistry and the recipient of this year’s prestigious John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry–addressed conference attendees from around the world. During his lecture, he traced the evolution of liquid chromatography–mass spectrometry (LC–MS), framing it not just as a technical journey but also as a collective effort.

Thermo Fisher Launches Two New Mass Spectrometers at ASMS

Caroline Hroncich

At Monday’s Thermo Fisher Scientific’s press event during the American Society for Mass Spectrometry (ASMS) Conference in Baltimore, Maryland, the company introduced two new mass spectrometers—the Orbitrap Astral Zoom and the Orbitrap Excedion Pro—designed to advance research in proteomics, biopharmaceutical development, and complex disease biology. According to the company, the instruments offer improvements in analytical speed, resolution, and throughput, targeting areas where deeper insights into biological data are increasingly essential, particularly in studies of diseases such as Alzheimer’s disease and cancer.

Sciex Launches New Mass Spectrometry System at ASMS in Baltimore

Caroline Hroncich

At this week’s American Society for Mass Spectrometry (ASMS) Conference in Baltimore, Maryland, Sciex presented updates to its mass spectrometry product lineup, focusing on tools for quantitative analysis in omics research. The main announcement was the ZenoTOF 8600 system, a mass spectrometer designed to provide rapid, high-resolution analysis of thousands of molecular species in complex biological samples. The system targets applications across proteomics, metabolomics, and genomics.

Industry Leaders Urge New Scientists to Embrace—and Challenge—Innovation

Caroline Hroncich

From handmade machines to high-throughput powerhouses, mass spectrometry (MS) has undergone a dramatic transformation—and so has the American Society for Mass Spectrometry (ASMS) conference over its 73-year history. At this year’s meeting, LCGC sat down with executives from top analytical science and technology companies to discuss emerging trends and professional insights. As part of these conversations, we asked: What advice should early-career analytical chemists be paying close attention to right now?