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While conventional calibration for gel permeation (GPC) and size-exclusion chromatography (SEC) are useful for polymer characterization, there are inherent disadvantages in these analyses. Adding multi-angle light scattering (MALS) detection can help overcome the challenges faced with single-detector chromatography. For more complex polymers, asymmetric flow field-flow fractionation (AF4) offers additional capabilities. This e-book explains what you need to know about using MALS in polymer analysis.