Development of a High-Throughput LC/MS/MS Assay for 13 Commonly Prescribed Pain Management Drugs from Urine with Cleanup Using Solid Phase Extraction (SPE)

Article

E-Separation Solutions

E-Separation SolutionsE-Separation Solutions-07-20-2010
Volume 0
Issue 0

Utilizing the ultra-high efficiency provided by core-shell technology columns, thirteen pain management opioids were resolved in 1.5 minutes with one second wide peaks at base on a Kinetex? C18 2.6 ?m 50 x 2.1 mm column.

External Link - article-680044.pdf

Articles in this issue
Development of a High-Throughput LC/MS/MS Assay for 13 Commonly Prescribed Pain Management Drugs from Urine with Cleanup Using Solid Phase Extraction (SPE)
Food Analysis/Quality
Food Analysis/Quality
Recent Videos
Ilaria Belluomo, Giorgia Purcaro, and Katelynn Perrault Uptmor © Images courtesy of interviewees
Woman with science © Aleksey - stock.adobe.com.
Related Content
Pressed grape pomace, seeds and skins. Winemaking background. | Image Credit: © aquatarkus - stock.adobe.com

Extracting Grape Pomace Compounds with Two-Dimensional Liquid Chromatography

Aaron Acevedo
June 12th 2025
Article

Grape pomace, a byproduct of the winery industry, holds various phenolic compounds within it. Scientists used liquid chromatography-based techniques to harvest these potentially beneficial components.

Ep. 37: On the Subject of Flow Imaging Microscopy in Collaboration with the American Association of Pharmaceutical Scientists

Ep. 37: On the Subject of Flow Imaging Microscopy in Collaboration with the American Association of Pharmaceutical Scientists

June 2nd 2025
Podcast

In episode #37 of Analytically Speaking, podcast host Dr. Jerry Workman speaks with Dr. Austin Daniels, application scientist for Yokogawa Fluid Imaging Technologies, about flow imaging microscopy (FIM), a new technology for sub-visible particle characterization in biologics.

Site Logo

Methods for Pharmaceutical Analytes and Oligonucleotides Using Elevated pH Conditions

June 12th 2025
Article

Ep. 36: A Day in the Life of a NIST Scientist

Ep. 36: A Day in the Life of a NIST Scientist

May 14th 2025
Podcast
Transparent green molecules background, 3d rendering. | Image Credit: © Vink Fan - stock.adobe.com

Simplifying Molecular Simulations Simplified with a Workflow Management System

Aaron Acevedo
June 11th 2025
Article

Molecular simulations, while useful in chromatographic biomolecule analysis, can be complex to set up and run. Researchers aimed to simplify these processes using two workflow management systems.

Burgruine Hambach am Niederrhein nahe Jülich | Image Credit: © mitifoto - stock.adobe.com

Optimizing Hydrophobic Interaction Chromatography for Protein Elution

Aaron Acevedo
June 11th 2025
Article

Hydrophobic interaction chromatography (HIC) is useful, albeit costly, for purifying proteins. Researchers aimed to reformulate HIC isotherms using salt-dependent water activity to optimize the process.