Evaluation of a Novel Composite Silica Technology for Solid Phase Extraction

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The Microlute® CSi products use a novel composite technology which uses a blend of porous plastic and chromatographic SPE resin. This technology has been designed to eliminate issues caused by inherent issues and inconsistent packing of loose packed SPE plates. The data in this application note compares SPE results from a C18 10 mg loose packed plate with a C18 10 mg composite plate (Microlute® CSi) which were both created using the same batch of C18 resin.