Extension of TSK-GEL ODS-100 reversed phase column line
Tosoh Bioscience is extending the portfolio of TSK-GEL ODS-100 reversed phase columns by a new 3µm TSKgel ODS-100Z stationary phase and additional column dimensions for all TSK-GEL ODS-100 phases.
Tosoh Bioscience is extending the portfolio of TSK-GEL ODS-100 reversed phase columns by a new 3µm TSKgel ODS-100Z stationary phase and additional column dimensions for all TSK-GEL ODS-100 phases. TSKgel ODS-100V and TSKgel ODS-100Z columns incorporate best-in-class surface properties to limit secondary interactions of basic, acidic and chelating compounds. They offer high efficiency and symmetrical peak shapes.
TSK-GEL ODS-100Z columns offer strong retention and high selectivity when separating homologues series of non-polar and polar compounds. They contain a high density monomeric C18 bonded phase for maximum retention of small molecular weight compounds. When using low pH mobile phase conditions, TSK-GEL ODS-100Z columns outlast other RP columns by providing stable retention. This popular C18 phase is now available in 3µm particle size. For both, 3µm and 5µm particle size the choice of available column dimensions was expanded.
TSK-GEL ODS-100V columns provide strong retention and high selectivity for polar solutes. The TSKgel ODS-100V stationary phase is less hydrophobic than ODS-100Z phase. Monomeric bonded phase chemistry and highly efficient endcapping provides complete wetting and retention stability in 100% aqueous mobile phases. Due to continued requests 3 mm ID and other lengths were added to the existing 2 and 4.6 mm ID TSKgel ODS-100V, 3µm and 5µm column line.
A new brochure on reversed phase chromatography provides detailed information on the broad range of TSK-GEL reversed phase columns. Visit www.tosohbioscience.com to download the brochure or to order your personal copy.
Measuring Procyanidin Concentration in Wines Using UHPLC
January 24th 2025Researchers from the University of Bordeaux (Villenave d'Ornon, France) report the development and validation of a rapid and quantitative analytical method measuring crown procyanidin concentration in red and white wines using ultra-high performance liquid chromatography (UHPLC) coupled with a ultra-high performance liquid chromatography (Q-TOF) mass spectrometer.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Testing Solutions for Metals and PFAS in Water
January 22nd 2025When it comes to water analysis, it can be challenging for labs to keep up with ever-changing testing regulations while also executing time-efficient, accurate, and risk-mitigating workflows. To ensure the safety of our water, there are a host of national and international regulators such as the US Environmental Protection Agency (EPA), World Health Organization (WHO), and the European Union (EU) that demand stringent testing methods for drinking water and wastewater. Those methods often call for fast implementation and lengthy processes, as well as high sensitivity and reliable instrumentation. This paper explains how your ICP-MS, ICP-OES, and LC-MS-MS workflows can be optimized for compliance with the latest requirements for water testing set by regulations like US EPA methods 200.8, 6010, 6020, and 537.1, along with ISO 17294-2. It will discuss the challenges faced by regulatory labs to meet requirements and present field-proven tips and tricks for simplified implementation and maximized uptime.
