This application note describes a method for the rapid and simultaneous quantitation of benzene, 1,4-dioxane, and formaldehyde in personal care products (PCPs). Nine retail hair and skincare products from the United Kingdom were analyzed, with limits of quantitation (LOQs) for benzene in the low-ng g−1 range and 1,4-dioxane and formaldehyde in the sub- and low- μg g−1 range, respectively. Preliminary results indicate that SIFT-MS holds an 8- to 30-fold throughput advantage when compared to conventional gas chromatography (GC-MS).
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.
The Power of HPLC/SFC Control and AQbD in One Software
July 17th 2024Download this infographic for a quick overview of Shimadzu’s LabSolutions Method Development (MD) software, an effective and automated software solution for U/HPLC method development that uses analytical quality by design (AQbD) principles in its workflow.