Introducing the flexible Contichrom® lab process equipment
Introducing the flexible Contichrom® lab process equipment
Contichrom® lab is a preparative 2-column liquid chromatography system designed for discovery, process development and scale-up, offering great flexibility for all process choices (batch, SMB, MCSGP, multi-column) using a single equipment and control software.
Fast process development for an optimized process is being achieved by omitting large screening efforts and instead starting from a simple non-optimized batch process that is switched to a superior MCSGP process by the user-friendly Contichrom® lab control software.
The MCSGP process principle uses twin columns instead of one, whereby the impure side fractions containing product are recycled internally extracting all product, thereby increasing both yield and purity by 50% at a 10-fold throughput increase and 70% buffer reduction.
All standard resin and column formats (RP, HIC, IEX, SEC) can be used from low-high pressure with full solvent compatibility.
Contichrom® lab has been designed to be very user-friendly employing software that helps the user to navigate through the process setup, execution and reporting, being 21CFR part 11 compliant.
Is your LC purification system equally adaptable?
Learn more about LC purification with Contichrom at http://www.knauer.net/contichrom
Inquiries: ref="mailto:info@knauer.net">info@knauer.net
Identifying and Rectifying the Misuse of Retention Indices in GC
December 10th 2024LCGC International spoke to Phil Marriott and Humberto Bizzo about a recent paper they published identifying the incorrect use of retention indices in gas chromatography and how this problem can be rectified in practice.
Overcoming Common Challenges to Determine Residual Impurities Using IC in APIs with Limited Water
December 10th 2024Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.