DryLab 4 is the next generation UHPLC modeling software. With its comprehensive resolution and robustness mapping abilities, DryLab 4 offers an intuitive and visual solution for method development, optimization, trouble-shooting, robustness testing, and training.
DryLab 4 is the next generation (U)HPLC modeling software. With its comprehensive resolution and robustness mapping abilities, DryLab 4 offers an intuitive and visual software solution for method development, optimization, trouble-shooting, robustness testing, and training. DryLab 4’s 3D modeling capabilities and its multifactorial evaluation of flow rate, column dimensions, instrument parameters, and eluent composition in gradient and isocratic work, provide users with the tools to easily conform to Quality by Design standards. A further robustness evaluation helps users to find the robustness thresholds of their method, and determines which parameters exert the most influence on the critical resolution.
Our latest DryLab 4 feature, the Knowledge Management reporting tool, generates a complete method report, including the Design of Experiments, the 3D model, the robustness calculations, the comparison in retention times between the experimental and predicted outcomes, and all justifications for the method choices. This software tool encourages users to follows a QbD approach to method development, and helps ensure that the completed method conforms to these standards.
Website:
www.molnar-institute.com
Transferring Methods to Compact and Portable HPLC
February 14th 2024The current trend in laboratory equipment design is the miniaturization of laboratory instruments. Smaller-scale HPLC instruments offer benefits that cannot be matched by analytical-scale equipment, especially in the areas of portability, reduced fluid volumes, and reduced operating costs. Yet, the miniaturization of laboratory equipment has brought with it a unique set of challenges, including transferring methods to compact LC. Capillary LC expands the use of LC to applications not currently done using conventional LC in a wide array of application areas, including pharmaceutical, food and beverage, petrochemical, environmental, and oil and gas. Greg Ward, Axcend’s CEO wrote, “Customers want an HPLC system with a small footprint, low flow rates and green chemistry.” Join his podcast where he shares method transfer in these application areas.