Improved High Temperature Simulated Distillation (ASTM D6352 and D7169) Using Zebron™ ZB-1XT SimDist Metal GC Columns
An improved method for high temperature simulated distillation based upon ASTM D7169 is presented using the Zebron ZB-1XT SimDist column. This column utilizes a Glass Infusion™ Technology that results in more improved efficiency, resolution, and unmatched column-to-column reproducibility. This technology also allows simulated distillation methods, such as ASTM D6352 and D7169, to be extended from C100 to C120 while still meeting all the system suitability requirements.
HPLC 2025 Preview: The Road To Sustainable Analytical Chemistry
May 20th 2025Elia Psillakis from the Technical University of Crete, Greece, and winner of this year’s Silver Jubilee Award from the Chromatographic Society, which will be presented at HPLC 2025, gives an update on current initiatives in green analytical chemistry.
Hydrophilic Interaction Chromatography (HILIC) and Direct Online Disruption of Lipid Nanoparticles
May 19th 2025Two proof-of-concept hydrophilic interaction chromatography HILIC) methods were developed in a joint study conducted by the University of Geneva (Switzerland), Sanofi, and the Waters Corporation—one for disrupting LNPs and retaining the mRNA, and another for detecting only unencapsulated mRNA to assess encapsulation efficiency. LCGC International spoke to Jonathan Maurer, first author of the paper that resulted from this study, about the methods and the efforts that led up to their development.
