Agilent Product Profile
Introducing the Agilent 1290 Infinity LC with Intelligent System Emulation Technology (ISET)—the world's first truly universal LC system.
ISET boosts productivity
Accelerate your instrument-to-instrument method transfer
No more method transfer problems! Simply emulate the LC system on which the original method was developed.
Achieve higher productivity for method development
Speed up your method development with UHPLC performance and then fine-tune your method by emulating the target system with confidence.
Make a safe investment for the future
Run your legacy HPLC methods with ISET and benefit from UHPLC performance with new methods. No need to maintain your old legacy LC systems.
To learn more visit www.agilent.com/chem/iset
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.