LECO's holistic HRT approach offers ease of operation, sensitivity, confident data generation and continuity in your laboratory. Accuracy, Resolution & Speed are delivered by CITIUS&£153; LC-HRT and Pegasus® GC-HRT — Without compromise.
Imagine a flexible system with Ultra High Resolution modes at your finger tips, High Mass Accuracy with confidence, full mass range spectra with efficient and High Speed detection. This is not imagination. This is reality with the CITIUS LC-HRT mass spectrometer, truly an instrument worthy of the Gold Award.
High resolving power is essential for separating strong matrix interferences from analytes of interest and allows lower detection limits to be achieved. CITIUS LC-HRT benefits from outstanding Ultra High Resolution (R = 100000) and High Mass Accuracy (
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.