MALDI imaging
MALDI imaging is a technique that allows the direct visualization of drugs and metabolites in tissue.
Visualize the distribution of drugs and metabolites in tissue without the time and expense of radiolabels or molecular tags!
MALDI imaging is a technique that allows the direct visualization of drugs and metabolites in tissue. One of the latest developments in this field is the seamless integration of MALDI imaging and virtual microscopy to provide detailed histopharmacology.
Because MALDI imaging uses mass spectrometry to detect targets, the distribution of each unique molecular formula can be monitored separately. The power of MALDI imaging combined with histology MALDI can help answer important questions such as:
See examples from real life DMPK research in this review article:
Castellino S, Groseclose MR, Wagner D (2011), MALDI imaging mass spectrometry: bridging biology and chemistry in drug development. Bioanalysis. 3(21):2427-41 http://www.future-science.com/doi/abs/10.4155/bio.11.232
See here a real-time demonstration of how histology and MALDI drug imaging are integrated in an easy and intuitive way: http://www.youtube.com/watch?v=eyyAIFHlrg0
Click here for more information about MALDI Imaging!
Contact us: ref="http://www.bruker.com/maldiimaging">www.bruker.com/maldiimaging
Targeted Blood Lipidomics of Colorectal Cancer: An HTC-18 Interview with Jef Focant
July 26th 2024At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Jef Focant from the University of Liege about his talk entitled, “Targeted Blood Lipidomics of Colorectal Cancer."
Carol Robinson Awarded 2024 Lifetime Achievement European Inventor Award
July 24th 2024Carol Robinson of the University of Oxford has received the European Inventor Award 2024 for Lifetime Achievement from the European Patent Office for her work bringing mass spectrometry to structural biology.
