Monday morning sessions
Monday Morning Sessions
HPLC 2011 kicks off to a great start with a series of keynote lectures chaired by Peter Schoenmakers. Gyula Vigh opens this session with a lecture on a new preparative-scale isoelectrophoretic trapping device and is followed by Guenther Bonn talking about the importance of novel enrichment and separation methods in bioanalysis. Massimo Morbidelli closes this session with a lecture on continuous chromatography (MCSGP) for the purification of therapeutic proteins.
Mark Schure chairs the Particle Technology session that includes a lecture from Fabrice Gritti on the challenges that need to be overcome to develop more efficient columns and technologies. The session closes with a talk by Tivadar Farkas on the performance of commercial HPLC columns made with core-shell sorbent particles.
Klára Valkó hosts the DNA and Biopharmaceuticals session that starts with a talk by Edward Yeung on the electromigration of single protein and DNA molecules in nanopores followed by a lecture on biointeraction analysis by high performance frontal affinity chromatography by Temporini Caterina. An overview of new separation media and methods for plasmid DNA analysis is presented by Michael Laemmerhofer and Frank Tomasella closes the session with a talk on quality by design in the development of an analytical chromatographic method.
The Proteomics session chaired by Robert Kennedy begins with a talk by Barry Karger on the ultra-trace proteomic analysis of 10,000 laser capture microdissection breast cancer cells using 2D LC–MS with a PLOT column followed by Alejandro Cifuentes on the future of foodomics; Sebastiaan Eeltink on the potential of polymer monolithic column technology combined with high-resolution MS to analyse protein isoforms and László Drahos on nanoUPLC–MS–MS to determine glycosylation patterns.
Poster sessions and vendor seminars take place during the lunch break.
Evaluating Antimicrobial Potential of Articaine Derivatives in Oral Infections with CMC
May 20th 2025Cell membrane chromatography (CMC) technology was used by researchers in screening efficacy and antibacterial ability of articaine (AT) derivatives in the pre-emptive treatment of oral infections.
Hydrophilic Interaction Chromatography (HILIC) and Direct Online Disruption of Lipid Nanoparticles
May 19th 2025Two proof-of-concept hydrophilic interaction chromatography HILIC) methods were developed in a joint study conducted by the University of Geneva (Switzerland), Sanofi, and the Waters Corporation—one for disrupting LNPs and retaining the mRNA, and another for detecting only unencapsulated mRNA to assess encapsulation efficiency. LCGC International spoke to Jonathan Maurer, first author of the paper that resulted from this study, about the methods and the efforts that led up to their development.
This article discusses how integrating seven prioritization strategies can enhance compound identification, support environmental risk assessment, and accelerate decision-making.