This morning session, which is chaired by X. Chris Lee of the University of Alberta, Canada, and starts at 8:30 a.m., will explore advances in high performance liquid chromatography and mass spectrometry for various aspects of environmental analysis, including new work being done by researchers in North America and Asia.
This morning session, which is chaired by X. Chris Lee of the University of Alberta, Canada, and starts at 8:30 a.m., will explore advances in high performance liquid chromatography and mass spectrometry for various aspects of environmental analysis, including new work being done by researchers in North America and Asia.
Keynote lecturer Susan Richardson of the University of South Carolina will kick off the session with a talk on the state of the art in chromatography and mass spectrometry methods for the analysis of emerging environmental contaminants.
Xing-Fang Li of the University of Alberta, Canada, will then deliver another keynote talk on integrating the power of chromatography and mass spectrometry for the discovery of peptides and halogenated peptides in water.
Zongwei Cai, of Hong Kong Baptist University, in Kowloon, Hong Kong, will then give a talk on mass-spectrometry–based metabolomics and imaging analysis in environmental toxicology research.
Guibin Jiang of the Chinese Academy of Sciences in Beijing will close out the session with a talk on the identification of new environmental contaminants by LC–MS.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
RP-HPLC to Compare Genotoxic Impurities in Extracted and Synthetic Nicotine
November 7th 2024A recent study examined the impurity profile of thirteen different lots of synthetic nicotine and compared them to fourteen lots of nicotine extracted from plants using in-house analytical methods, with samples tested for alkaloids and phenols with reversed-phase high-performance liquid chromatography (RP-HPLC).