Laura Bush

Laura Bush is a former managing editor of Pharmaceutical Technology. She is currently the Editor-in-Chief of BioPharm International, a sister publication of Pharmaceutical Technology. 485 Route One South, Building F, First Floor, Iselin, NJ 08830, lbush@advanstar.com, tel. 732.346.3020

Articles by Laura Bush

LC–MS techniques, particularly those using high-resolution MS and nontargeted analysis, are advancing many areas of water research. Here, Imma Ferrer of the University of Colorado shares some of her recent work in this field.

The potential of food packaging components to migrate into food is an important health concern. Perfecto Paseiro Losada and his group at the University of Santiago de Compostela, in Spain, have been investigating the migration kinetics and actual migration of such compounds into a variety of types of food. They also have been carrying out studies to estimate dietary exposure. Paseiro recently spoke to LCGC about this work.

In this interview, Thomas Letzel of the Technical University of Munich considers the current state of water analysis, looking at recommended techniques, the growth of nontargeted screening, and multi-disciplinary collaboration.

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When analytical chemists apply green chemistry approaches, which seek to minimize negative environmental effects, an important area of focus is reducing the consumption of toxic solvents, such as those used in extraction steps in sample preparation. Developing and testing greener extraction processes for food analysis is a major focus of Elena Ibáñez, a research professor at the Institute of Food Science Research (CIAL-CSIC) in Madrid, Spain.

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Elena Ibañez is determined to make sample preparation for food analysis not only more environmentally friendly but also more efficient, as she explores approaches that simplify solvent selection, increase solvent selectivity, and lessen the role of chemical solvents.

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Analytical chemists are always seeking to make method development more efficient. For nearly two decades, Chris Welch led his teams at the Merck & Co. to constantly drive innovation in this area. Following his recent retirement from the company last year, he and his colleagues wrote a paper about the current state of method development for pharmaceutical research and where it is heading. He recently spoke to us about this topic.

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When a company wishes to commercialize a new pesticide, they must conduct environmental studies and develop analytical methods capable of detecting the pesticide, and its metabolites, in soil and water samples. The methods must be robust and rugged, for easy use in routine analysis. James Stry, a principal investigator at FMC Agricultural Solutions, recently talked to LCGC about best practices he and his team have established for developing such methods, including approaches to meeting a variety of requirements of regulatory bodies, simplifying sample preparation, dealing with matrix effects, choosing an ionization method, and streamlining method development.

This morning session, which begins at 11:15 a.m., kicks off with a talk by Luis Colon of the State University of New York at Buffalo, on aminophenyl-derived phases on superficially porous silica particles.

This morning session, which is chaired by X. Chris Lee of the University of Alberta, Canada, and starts at 8:30 a.m., will explore advances in high performance liquid chromatography and mass spectrometry for various aspects of environmental analysis, including new work being done by researchers in North America and Asia.

The 2018 recipients of the John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry are Gert Von Helden, Martin F. Jarrold, and David E. Clemmer, for their pioneering contributions to the development of ion mobility spectrometry (IMS).

This second of the two parallel tutorial sessions on Sunday evening includes talks from Gregory Eiden of Pacific Northwest National Laboratory (PNNL) and Jack Beauchamp of California Institute of Technology.

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Specialists in food analysis are increasingly interested in taking advantage of methods that harness the power of ultrahigh-pressure liquid chromatography (UHPLC) and high-resolution mass spectrometry (HRMS). Jon Wong of the Center for Food Safety and Applied Nutrition at the U.S. Food and Drug Administration has been developing such methods for a variety of types of analysis. In this interview, he talks to LCGC about the work to develop these methods and the advantages of their use.