New Sample Preparation Approaches to Biological Matrices for LC–MS

LCGC North America, December 1999, Volume 17, Issue 12
Pages: 1084–1093

Columns | <b>Column: Sample Prep Perspectives</b>

This month's "Sample Prep Perspectives" column summarizes current sample preparation procedures for LC–MS as applied to samples from biological matrices. Guest columnist Fred Klink describes ion suppression effects and other interferences common in LC–MS to provide a basis for understanding sample preparation requirements. He also examines established procedures as well as new concepts in sample preparation.