Optimizing the Analysis of Sugar Alcohol Excipients in Pharmaceutical Tablet Formulations Using Rezex Ion Exclusion HPLC Columns
Sugar alcohols require unique methods for analysis by HPLC due to their high polarity and lack of a UV-absorbing chromophore. USP methods for these separations take advantage of ion exclusion HPLC techniques. In this note, several different separations of sugar alcohols were performed using ion exclusion Rezex RPM and RCU HPLC columns.
Study: GC-MS to Investigate Toxicology Following Italy Prison Riots
October 4th 2024A recent study examined three drug overdose deaths resulting from an Italian prison riot during the initial wave of the SARS-CoV-2 pandemic. To ascertain the nature of these deaths, a comprehensive toxicological analysis was conducted, employing gas chromatography-mass spectrometry to reveal high concentrations of various substances in the biological fluids of the deceased inmates.
Pick Your Poison: Isolation of Paclitaxel (Octt 2024)
October 4th 2024The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.
