High-performance liquid chromatography-tandem mass spectroscopy (HPLC–MS/MS) chromatography reveals pyrrolizidine alkaloids (PA)/pyrrolizidine alkaloid N-oxides (PANO) toxin risks in 63 tea samples.
|Articles|October 23, 2019
Overcoming Separation Challenges in Biological Drug Development
Author(s)Advanced Materials Technology
The landscape for new biological drug development continues to evolve in complexity. With biosimilars entering the market and originator products coming off patent, the competitive race for market dominance is reliant on!
Related to this article
Advances in DNA/RNA chromatography columns led to stable, pure mRNA production, supporting the development of COVID-19 vaccines rapidly.
Steven Ray Wilson's AFFL LC–MS system runs thousands of injections per column, but he calls validation and standardization the field's real barrier.
Kinjal Bhatt and Ina Varfaj describe imposter syndrome fading through repeated exposure and conference talk rather than a single breakthrough moment.
Mass spectrometry can teach core chemistry concepts beyond technique training or product characterization, though adoption barriers remain.
Automated sequential tube sampling and chemometrics supplement GC–MS, adding time profiling and fast product-line comparison for real-world insight.
Ultrahigh-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) tracks blood metabolite changes after repetitive transcranial magnetic stimulation (rTMS)-cognitive training therapy.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.