Emma Macturk from LECO Corporation explains which forensic applications benefit from GC×GC’s greater peak capacity, and when the additional separation power may only provide limited benefits.
|Articles|March 5, 2010
Oxidative Metabolism of Acetaminophen Using ROXY EC System
Acetaminophen (paracetamol; APAP; IUPAC: N-(4-hydroxyphenyl)acetamide) was chosen as model drug to investigate oxidative metabolism using the ROXY EC System dedicated for single component screening. Electrochemical conversion of the acetaminophen into reactive phase I metabolites and the NAPQI ? GSH phase II conjugate was successfully achieved.
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