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Three Day Virtual Symposium: Separation Science- The State of The Art The Global Chemical Industries Summit The Power of CE-MS in Biotherapeutics Characterization Capillary Gas Chromatography: Getting the Best Separation Without Turning (Too Many) Wrenches The Hidden Factory in Your Laboratory?

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Three Day Virtual Symposium: Separation Science- The State of The Art
The Global Chemical Industries Summit
The Power of CE-MS in Biotherapeutics Characterization
Capillary Gas Chromatography: Getting the Best Separation Without Turning (Too Many) Wrenches
The Hidden Factory in Your Laboratory?

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Liquid Chromatography (LC/HPLC)
Gas Chromatography (GC)
Sample Preparation
Mass Spectrometry
Pharmaceutical Analysis
Environmental Analysis
Food and Beverage Analysis

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Oxidative Metabolism of Acetaminophen Using ROXY EC System

March 5, 2010

Acetaminophen (paracetamol; APAP; IUPAC: N-(4-hydroxyphenyl)acetamide) was chosen as model drug to investigate oxidative metabolism using the ROXY EC System dedicated for single component screening. Electrochemical conversion of the acetaminophen into reactive phase I metabolites and the NAPQI ? GSH phase II conjugate was successfully achieved.