LECO product profile
Routine Pegasus® 4D GCxGC-TOFMS optimisation is now even easier. Variable Modulation Times (VMT) feature was designed and implemented into LECO’s ChromaTOF® single software platform for even more flexibility. Traditional GCxGC uses a fixed modulation period and can result in an analytical compromise to the 1st dimension separation. The advantage of VMT enables the operator to specify at the click of a button their own and different modulation times throughout the GCxGC run. Typically, applications benefiting from GCxGC separations are matrix heavy &/or are complex samples containing a broad range of analytes. In such complex mixtures, early eluting and more volatile analytes actually require shorter modulation times whilst later eluting analytes (high boilers) require much longer modulation times. Using the new LECO VMT programming style results in graduated Pegasus 4D® GCxGC-TOFMS chromatograms in the 2nd dimension and so preserves the valuable separation in the first dimension. This feature maximizes resolution in both the first and second dimensions and is compatible with LECO’s traditional LN2 and Consumable Free (CF) Pegasus 4D® GCxGC-TOFMS instruments.
Join the experts in the field who routinely operate the Pegasus 4D® GCxGC-TOFMS and learn from their experiences. The 2nd European GCxGC Symposium takes place 20th & 21st September, University Regensburg, Germany. Registration is open, for more information contact the LECO Separation Science team.
Marie-Bernays-Ring 31
41199 Mönchengladbach
Germany
Tel: +49 (0)2166 687 -104 or -107
Email: SepSci@leco.de
Web address www.leco.com & www.leco-etc.com
Emerging Trends and Challenges in Detecting Residues and Contaminants in Food in the Exposome Era
June 18th 2025This article describes the analytical challenges of chemical exposomics in food safety. The need for high-throughput, multi-platform approaches—such as LC–HRMS and GC–HRMS with IMS—to capture the full spectrum of potential contaminants in our food supply is emphasised.
New Research Explores Role of Nucleotide Hydrophobicity in Oligonucleotide Separation
June 18th 2025Researchers from Waters and Biospring studied the contribution of nucleotide type and modifications on the retention and resolution of 22–24 nt long oligonucleotides in different chromatographic methods.
A Life Measured in Peaks: Honoring Alan George Marshall (1944–2025)
June 18th 2025A pioneer of FT-ICR Mass Spectrometry, Alan G. Marshall (1944–2025), is best known for co-inventing Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), a transformative technique that enabled ultrahigh-resolution analysis of complex mixtures. Over a career spanning more than five decades at institutions like the University of British Columbia, The Ohio State University, and Florida State University, he published over 650 peer-reviewed papers and mentored more than 150 scientists. Marshall’s work profoundly impacted fields ranging from astrobiology to petroleomics and earned him numerous prestigious awards and fellowships. Revered for his intellect, mentorship, and dedication to science, he leaves behind a legacy that continues to shape modern mass spectrometry.