Using solid-phase extraction sorbent followed by LC–MS–MS analysis using HILIC to measure melamine and cyanuric acid in under 3 mins.
The presence of both melamine and cyanuric acid in concentrations greater than 2 µg/mL results in the crystallization of the two compounds, forming the toxic, poorly water soluble melamine cyanurate complex. Increasingly, governing and regulatory bodies are requiring the testing of both melamine and cyanuric acid in processed food products. Many methods describing the simultaneous analysis of melamine and cyanuric acid have been published, however, to extract both compounds from food samples with the currently accepted method, analysts have to perform two solid-phase extraction procedures using a cation-exchange material and an anion-exchange material, for melamine and cyanuric acid respectively. This article describes a method for the simultaneous extraction of both compounds using one solid-phase extraction sorbent, Strata Melamine, followed by LC–MS–MS analysis using Luna HILIC to accurately measure melamine and cyanuric acid in less than 3 minutes.
Targeted Blood Lipidomics of Colorectal Cancer: An HTC-18 Interview with Jef Focant
July 26th 2024At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Jef Focant from the University of Liege about his talk entitled, “Targeted Blood Lipidomics of Colorectal Cancer."
Carol Robinson Awarded 2024 Lifetime Achievement European Inventor Award
July 24th 2024Carol Robinson of the University of Oxford has received the European Inventor Award 2024 for Lifetime Achievement from the European Patent Office for her work bringing mass spectrometry to structural biology.