A novel SFC–QTOF-MS method accurately detected 10 drugs in oral fluid, matching LC–MS/MS in 83 DUID cases while reducing run time by 42% and organic solvent use by 81%.
|Articles|May 1, 2000
- May 2000
- Volume 18
- Issue 05
- Pages: 478–487
Starting Out Right, Part VI – The Scouting Gradient Alternative
Author(s)John W. Dolan
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A scouting gradient is a separation run under a standardized set of conditions and can be used to determine the complexity of a sample and estimate the difficulty of the separation. John Dolan tells why he believes using a scouting gradient is the best way to begin method development.
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