Temperature Effects in GPC/SEC


Tips & Tricks: GPC/SEC

Temperature effects in GPC/SEC are very often misunderstood and discussed without keeping the specialties of GPC/SEC in mind. From a thermodynamic point of view the GPC/SEC separation mechanism is independent of the temperature. Therefore, there is no need to optimize the set-up for many applications with respect to temperature. However, the temperature influences the polymer solubility, the solvent viscosity and, therefore, the column performance. Consequently some applications require better knowledge about the influence of the temperature on these parameters.

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