Tips & Tricks: GPC/SEC
Temperature effects in GPC/SEC are very often misunderstood and discussed without keeping the specialties of GPC/SEC in mind. From a thermodynamic point of view the GPC/SEC separation mechanism is independent of the temperature. Therefore, there is no need to optimize the set-up for many applications with respect to temperature. However, the temperature influences the polymer solubility, the solvent viscosity and, therefore, the column performance. Consequently some applications require better knowledge about the influence of the temperature on these parameters.
Study: GC-MS to Investigate Toxicology Following Italy Prison Riots
October 4th 2024A recent study examined three drug overdose deaths resulting from an Italian prison riot during the initial wave of the SARS-CoV-2 pandemic. To ascertain the nature of these deaths, a comprehensive toxicological analysis was conducted, employing gas chromatography-mass spectrometry to reveal high concentrations of various substances in the biological fluids of the deceased inmates.
Pick Your Poison: Isolation of Paclitaxel (Octt 2024)
October 4th 2024The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.