Lorna Nisbet from the Leverhulme Research Centre for Forensic Science, discusses a GC–MS. technique developed to detect anabolic-androgenic steroids in e-cigarettes seized from Scottish prisons.
|Articles|November 19, 2010
Waters SFC Episode 3:Preparative SFC
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Supercritical Fluid Chromatography in Theory and Practice
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Episode 3: Preparative SFC
Considered a leading “green” purification technology, SFC systems are used to separate, isolate and purify chemical compounds. The principles of SFC are similar to those of liquid chromatography; however SFC typically uses carbon dioxide as the main mobile phase. Carbon dioxide offers environmental and cost benefits compared to traditional liquid chromatography solvents. In this episode we will provide an overview of Preparative SFC, and the advantages it brings to today’s chemical processes.
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Kinjal Bhatt and Ina Varfaj trace their pull toward analytical science to a saturated chromatography peak and the moment their first chiral peaks separated.
Gérard Hopfgartner explains why pairing SFC with dopant-assisted APPI can match, or even beat, electrospray sensitivity, even at microflow LC rates.
Emma Macturk from LECO Corporation explains which forensic applications benefit from GC×GC’s greater peak capacity, and when the additional separation power may only provide limited benefits.
Koji Yamaguchi of the International University of Health and Welfare (Narita, Japan) discusses a novel derivatized liquid chromatography-tandem mass spectrometry (LC-MS/MS) method plus propofol glucuronide (PRG) marker which improves forensic propofol detection.
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Liquid chromatography-tandem mass spectrometry (LC-MS/MS) identifies blood metabolite patterns tied to children's diets.
Kirstine Nielsen of Aarhus University (Denmark) discusses how targeted metabolomics ratios helped build a robust bloodstain time-since-deposition tool.
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