Wednesday Afternoon Session Preview: Forensic Applications

June 5, 2013

E-Separation Solutions

This Wednesday afternoon session will include discussion of LC?MS analysis of cathinones in urine, ESI-MS analysis of compounds in mahogany wood, MS with a dual ionization source for analyzing a drug, a species-specific dating technique for human bone, forensic analysis of polymorphisms in hair shaft protein, and LC?MS-MS analysis of opioids in urine.

Wednesday, 2:30 - 4:30 PM, Exhibit Hall A

This Wednesday afternoon session will include discussion of LC–MS analysis of cathinones in urine, ESI-MS analysis of compounds in mahogany wood, MS with a dual ionization source for analyzing a drug, a species-specific dating technique for human bone, forensic analysis of polymorphisms in hair shaft protein, and LC–MS-MS analysis of opioids in urine.

The first presentation will be given by Sebastien Anizan of NIDA/NIH (Baltimore, Maryland). Anizan will discuss the first validated LC–HR MS method for the simultaneous quantification of 28 bath salts in urine. The presentation is titled “Development and Validation of a Liquid-Chromatography-High Resolution Mass Spectrometry Method for the Simultaneous Analysis of 28 Synthetic Cathinones in Urine.”

Marcos Eberlin of the University of Campinas (Campinas, Brazil) will present the next talk, titled “Differentiation of African and Brazilian mahogany wood Based on the Chemical Profile of Methanolic Extractives by Electrospray Ionization Mass Spectrometry.” His presentation will describe an ESI-MS technique that allows fast and accurate differentiation between Brazilian and African mahogany.

The next presentation in the session, “Analysis of Propofol (2,6-Diisopropylphenol) and Its Metabolites in One Injection Using a Dual Ionization Source,” will be given by Adrian Taylor of AB Sciex (Concord, Canada). He will discuss the analysis of Phase II, I, and parent drug and elucidation of ion structures.

Christopher Rollman of the Smithsonian Institution (Suitland, Maryland) next will present “Development of Species Specific Dating Technique for Human Bone with Minimal Sample Consumption.” The talk will describe a dating technique for bone ranging in age from present to >100,000 years.

Glendon Parker of Utah Valley University (Orem, Utah) will then present a talk titled “Identification of Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in Hair Shaft Protein and Utilization to Obtain Measures of Identity.” Parker will discuss how the study lays a foundation for using proteomics to genetically identify individuals in a forensic and legal context.

The session’s final presentation, to be given by Marc Rumpler of the University of Florida (Gainesville, Florida), is titled “LC-MS/MS Analysis of Opioids in Urine: Evaluation of LC-MS/MS Conditions for Interferences Due to Oxycodone Metabolites.” His talk will describe the assessment of interferences produced by oxycodone and its metabolites in urine.