The Pittsburgh Conference (Pittsburgh, Pennsylvania) has announced that George M. Whitesides, the Woodford L. and Ann A. Flowers University Professor of the Department of Chemistry and Chemical Biology at Harvard University (Cambridge, Massachusetts), will be the Plenary Speaker at Pittcon 2009 on March 8, 2009.
The Pittsburgh Conference (Pittsburgh, Pennsylvania) has announced that George M. Whitesides, the Woodford L. and Ann A. Flowers University Professor of the Department of Chemistry and Chemical Biology at Harvard University (Cambridge, Massachusetts), will be the Plenary Speaker at Pittcon 2009 on March 8, 2009. Pittcon 2009 will be held in March 8-13 in Chicago, Illinois. Whitesides' research interests include physical and organic chemistry, materials science, biophysics, complexity and emergence, surface science, microfluidics, optics, self-assembly, micro- and nanotechnology, science for developing economies, catalysis, origin of life, and cell-surface biochemistry.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
GPCRs – The Biological Traffic Modulator: Chromatographic Analysis of Peptides in the GI Tract
January 20th 2025The G protein-coupled receptors (GPCR) are found throughout the entire body and have shown significance in the development of new therapeutic treatments. Isolation of seven classic GRPC peptides initiating in the GI tract highlights the benefits of using the polymer-based PRP-3, a reversed-phase resin. The covalent bonds found in the PRP-3 exhibit advantageous interactions between the biological π bonds found in the peptides and the available aromatic benzyl rings of the resin.