Application Notes: General

• Characterizing cannabis • Terpenes analysis using headspace solid-phase microextraction and GC–MS • LC triple-quad and GCxGC-TOFMS for efficient cannabis testing.

With Antec Scientific’s new ground-breaking µ-PrepCell-SS, electrochemical reduction of disulfide bonds in peptides, proteins, mAbs, and other biopharmaceuticals becomes possible routinely in LC-MS workflows. • Fast and efficient reduction of S-S bonds • Robust on-line reduction in top-down and bottom-up Proteomics • Reagent free, no interfering DTT or TCEP, ideal for HDXMS • Superior peptide sequencing and S-S bond assignment

An effective enrichment method for glycopeptides were developed based on iSPE®-HILIC material. It opens a range of opportunities for glycoproteomics research.

Testing shows that Restek Long-Life ESI electrodes for Sciex Turbo V sources provide equivalent chromatographic performance to original equipment manufacturer electrodes over significantly longer lifetimes.

An efficient separation of polar and nonpolar lipid representatives was achieved utilizing iSPE®-HILIC material. The lipids were separated according to their polarity.

• Disaster recovery and business continuity plans are crucial for companies. • Most laboratories are not confident in their recovery and continuity plans. • When seeking solutions for system failures, consider regulatory guidelines.

Note discusses how labs are coping with the worldwide helium shortage.

In this application we show how to achieve the best separation and sensitivity for insulin UHPLC-MS analysis by using formic acid as a weak ion pairing agent.

This application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and Hydrobenzoin as a test compound.