Application Notes: General

What you will learn: - Automated extraction method achieves higher recoveries - Steps involved in QuEChERs vs. EDGE method

-Automated SIFT–MS increases productivity for thermal desorption tube analysis. -Case studies show that TD–SIFT–MS improves analysis for several applications.

Pickering Laboratories developed an easy and sensitive method to analyze aflatoxins B1, B2, G1, G2, and ochratoxin A in hemp and hemp-containing edible products. Mycotoxins are isolated using immunoaffinity clean-up columns and analyzed with fluorescence detection. To increase sensitivity of aflatoxins B1 and G1, an in-line photochemical reactor (UVETM) is installed before the detector. This method utilizes standard HPLC equipment and allows laboratories to easily determine these mycotoxins at low ppb levels.

-Overview of international guidances for data integrity -Insight into PIC/S guidances -Challenges of managing documentation

• Solutions for comparing innovator and biosimilar mAbs • Biosimilar case studies

• Data security in electronic versus paper environments • Division of responsibilities between users and vendors • Specific payment plans can provide advantages to meet financial goals.

Automated QuEChERS clean-up of hemp oil extracts combined with liquid introduction and PTV-GC–MS determination of pesticides leads to improved throughput and low LOQs.

This application note adopted the Full Evaporation Technique (FET) to analyze the solvent residual, based on California Residual Solvents Category, in cannabis oil.

The ability to predict multiple constituents of a final dosage form in one fast, nondestructive measurement can reduce analysis time and cost significantly.

• Acquiring laboratory equipment raises a number of challenges and concerns. • Specific payment plans can provide advantages to meet financial goals.

· Traps and “delays” system-related PFAS, preventing interference · Allows accurate identification and quantitation of trace-level PFAS · Highly retentive-no breakthrough even with extended equilibration times

This work shows how thermal desorption with GC–MS is used to measure volatile organic biomarkers in the breath of individuals with malaria.

A sensitive, robust method for analysis of glyphosate in wide range of foods using a simplified sample preparation procedure effective for challenging matrices

Fast and sensitive HPLC method with post-column derivatization for analyzing Fumonisins in grains and feeds at levels as low as 0.01 ug/g

A sensitive method for testing of active compounds in cannabis and cannabis-containing products.

A solution for amino acids analysis, these methods were optimized to comply with system suitability requirements of Pharmacopoeia 8.0 methods.

Highly sensitive analysis of aflatoxins and ochratoxin A to guarantee the safety of hemp crop and hemp-containing consumer products.

An easy and sensitive method to analyze Aflatoxins B1, B2, G1, G2 and Ochratoxin A in cannabis plant and edible products at levels below established by state regulations.

A sensitive HPLC method allows analyzing cannabinoids, including THC and CBD, in hemp and hemp-containing products to ensure compliance with the 2018 Farm Bill.