Advanced Topics in Solid-Phase Extraction: Chemistries
Although the majority of solid-phase extraction (SPE) is performed with conventional bonded silica- and polymeric-phases, difficult and complex samples may require more specialized stationary phases. In this instalment of "Sample Preparation Perspectives", columnist Ron Majors discusses advanced topics such as multimodal SPE, restricted-access media, molecular imprinted polymers, immunoaffinity extraction phases and other class-or compound-specific sorbents. These phases provide additional selectivity and procedures using them can be automated. Representative applications will be presented.