Showa Denko America | Authors

MALS with SEC improves the efficiencies of the analysis of bionanoparticles that are difficult to be differentiated from the impurities during the purification process. 

Due to the highly polar nature of saccharides, the analysis of sugars is typically achieved using Hydrophilic Interaction Chromatography (HILIC). Using a high polarity packing material, separation is based on the hydrophilic interactions of the sugars on the stationary phase surface typically using an eluent with a majority of polar organic solvent.

Due to the highly polar nature of saccharides, the analysis of sugars is typically achieved using hydrophilic interaction chromatography (HILIC).